Mississippi direct-to-consumer compliance, guide 22 of 24

Supplements

Dietary supplements fall under federal law; Mississippi publishes no cottage path.

Federal Rules Apply

DSHEAgoverns supplement claims and labels

cGMP21 CFR Part 111 manufacturing rules

15 daysbusiness-day serious event reporting

Nonecottage path in Mississippi

What is covered

A
Check your ingredients
Confirm each ingredient may lawfully be used in a supplement and keep the supporting documentation.
B
Manufacture to cGMP
Federal good manufacturing practice applies; many small brands use a contract manufacturer.
C
Label and report
Use Supplement Facts and a compliant claim statement; report serious adverse events to FDA within 15 business days.

Item	Rule	Regulator
Manufacturing	Current good manufacturing practice for supplements	FDA 21 CFR 111
Claims	No disease claims; structure or function claims need notice and disclaimer	FDA / FTC
Labeling	Supplement Facts panel, ingredients, net quantity, maker address	FDA
Adverse events	Serious events reported within 15 business days	FDA
State license	None located in research; confirm with MSDH	MSDH
Cottage food	Not on the list; supplements are not cottage foods	MSDH

Not under Mississippi's cottage law, and federal supplement manufacturing rules still apply.

That is a structure or function claim with notice and disclaimer duties. Avoid disease claims.

No state-specific rule was located. Confirm with MSDH.